@Article{SilvaZanVicCorFat:2015:ElDeRo,
               author = "Silva, Tiago Almeida and Zanin, Hudson G. and Vicentini, Fernando 
                         Campanha and Corat, Evaldo Jos{\'e} and Fatibello Filho, 
                         Orlando",
          affiliation = "{Universidade Federal de S{\~a}o Carlos (UFSCar)} and 
                         {Universidade do Vale do Para{\'{\i}}ba (UNIVAP)} and 
                         {Universidade Federal de S{\~a}o Carlos (UFSCar)} and {Instituto 
                         Nacional de Pesquisas Espaciais (INPE)} and {Universidade Federal 
                         de S{\~a}o Carlos (UFSCar)}",
                title = "Electrochemical determination of rosuvastatin calcium in 
                         pharmaceutical and human body fluid samples using a composite of 
                         vertically aligned carbon nanotubes and graphene oxide as the 
                         electrode material",
              journal = "Sensors and Actuators B: Chemical",
                 year = "2015",
               volume = "218",
                month = "May",
             keywords = "Biological samples, Carbon-carbon composite, Graphene oxide, 
                         Pharmaceutical samples, Rosuvastatin calcium, Vertically aligned 
                         carbon nanotubes.",
             abstract = "A novel electrochemical method for the determination of 
                         rosuvastatin calcium (RC) using a composite of vertically aligned 
                         carbon nanotubes and graphene oxide (VACNT-GO) as the electrode 
                         material is proposed. The VACNT-GO electrode was synthesized using 
                         a microwave-assisted chemical vapor deposition method followed by 
                         oxygen plasma treatment. The VACNT-GO electrode presented 
                         superhydrophilic behavior and fast charge transfer, which are very 
                         attractive for electrochemical applications. The RC molecule 
                         presented an oxidation process at +1.26 V vs. Ag/AgCl (3.0 mol L-1 
                         KCl) in phosphate buffer solution (pH 2), and this redox behavior 
                         was explored for its voltammetric determination. Using square-wave 
                         adsorptive anodic stripping voltammetry (SWAdASV) under optimized 
                         conditions, the analytical curve was linear in RC concentration 
                         range from 0.48 to 46.72 \μmol L-1 with a limit of detection 
                         of 0.06 \μmol L-1. The developed SWAdASV method was applied 
                         for RC quantification in commercial pharmaceutical samples, and 
                         the results are consistent with those obtained by the comparative 
                         spectrophotometric method at a confidence level of 95%. Moreover, 
                         RC was determined in human body fluid samples of urine and human 
                         serum.",
                  doi = "10.1016/j.snb.2015.04.085",
                  url = "http://dx.doi.org/10.1016/j.snb.2015.04.085",
                 issn = "0250-6874",
             language = "en",
           targetfile = "silva_electrochemical.pdf",
        urlaccessdate = "27 abr. 2024"
}